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Methods and compositions for detecting the activation of mtor pathway

The present invention relates to a method for measuring the activation of mTOR pathway in a subject suffering from a kidney disease associated with a […]

Ngal as a novel target for the treatment of chronic kidney disease

The severity of renal lesions after nephron reduction varied substantially among mouse strains and required activation of EGFR. Lipocalin 2 (Lcn2, […]

Cd9 as a new biomarker for diagnosing or predicting risk of

The mechanisms driving the development of extracapillary lesions in focal segmental glomerulosclerosis (FSGS) and crescentic glomerulonephritis (CGN) […]

Use of cd9 as a biomarker and as a biotarget in glomerulonephritis

The mechanisms driving the development of extracapillary lesions in focal segmental glomerulosclerosis (FSGS) and crescentic glomerulonephritis (CGN) […]

Primary cultures of mice proximal tubular cells

Proximal tubular cells are isolated by magnetic sorting coupled with microbeads-conjugated anti-Prominin-1 antibodies. Prominin-1 colocalizes with […]

Technique to isolate live renal proximal tubular cells from any mouse

We isolate renal proximal tubular cells using the proximal tubular marker Prominin-1. We use a 4°C, enzyme free protocole allowing high quality […]

Urinary peptidome analysis

In collaboration with Mosaiques Diagnostics we can analyse biofluid proteomes for your needs using capillary electrophoresis coupled to mass […]

Animal models of fibrosis

UUO: This model is induced in mice or rats by unilateral ureteral ligation (UUO) of the left ureter. The animals rapidly develop, within a few days, […]

Ppar-gamma agonist as target for the treatment of rapidly progressive

This study demonstrates the pivotal role of the local PPAR-gamma agonist system in maintaining podocyte quiescence and orchestrating the global […]

Periostin inhibitor in the prevention or treatment of chronic kidney

The present invention relates to an agent which binds to periostin selected from the group consisting of antibodies, aptamers, small organic molecules […]