ggggggggg

Mouse anti-human protein s (pros1) mabs

These mouse monoclonal antibodies are directed against human PROS1, an anti-coagulation factor. They are very specific and recognize 70-kDa protein. […]

Cardiac overexpression of the human beta3-adrenergic receptor.

Mice with a cardiac ovexpression of the human beta3-adrenergic receptor were produced by microinjection of a construct with A or C isoform gene under […]

Dba/1-abca1tm1jdm/j mice

The mutant ABC1 allele was generated by homologous recombination, by using a targeting vector containing a neomycin resistance and herpes simplex […]

Urinary peptidome analysis

In collaboration with Mosaiques Diagnostics we can analyse biofluid proteomes for your needs using capillary electrophoresis coupled to mass […]

Animal models of fibrosis

UUO: This model is induced in mice or rats by unilateral ureteral ligation (UUO) of the left ureter. The animals rapidly develop, within a few days, […]

Screening and characterization of new histone deacetylase inhibitors

Using BRET technology, we designed a method to measure histone acetylation in living cells. Cells are transfected with a vector coding for a […]

Scavenger receptor bi knockout mouse

The class B, type I scavenger receptor (Srb1 or Scarb1) is a cell surface HDL receptor. It plays a key role in determining the levels of plasma […]

Methods of treating heart failure

Worldwide, 1% to 2% of the general adult population have heart failure (HF), which is accompanied by reduced quality of life, high morbidity, […]

Methods and pharmaceutical compositions for cardiac regeneration

The adult mammalian heart regeneration is largely prevented by the limited proliferative capacity of the resident cardiomyocytes (CMs). Here, the […]

Methods and pharmaceutical compositions for the treatment of

The present invention relates to methods and pharmaceutical compositions for the treatment of age-related cardiometabolic diseases. In particular, the […]