Use of tcr-deficient car-tregs in combination with anti-tcr complex

The present invention is defined by the claims. In particular, the present invention relates to the use of TCR-deficient CAR-Tregs in combination with […]

Mesenchymal stem cell derived extracellular vesicles loaded with at

Several gastrointestinal and gynecological malignancies have the potential to disseminate and grow in the peritoneal cavity. The occurrence of […]

Correction of beta-thalassemia phenotype by genetically engineered

The present invention relates to a genetically modified hematopoietic stem cellrn(HSC) comprising, in at least one ?-globin gene comprised in the […]

Novel melanoma antigen peptide and uses thereof

The invention relates to peptides derived from the MELOE antigen for therapeutic vaccination against cancer. A phase I clinical trial for ex-vivo […]

Methods for expanding a population of alveolar macrophages in a long

The present invention relates to methods for expanding a population of alveolar macrophages in a long term culture. In particular, an object of the […]

Mitoception: novel method for the intracellular transfer of isolated

The present invention relates to a method for the intercellular transfer of an amount of mitochondria isolated from a population of donor cells into a […]

Pharmacologically active microcarriers for efficient integration of

This invention results from Pharmacologically Active Microcarriers (PAM) which are based on a biocompatible and biodegradable material. These […]