Use of tcr-deficient car-tregs in combination with anti-tcr complex monoclonal antibodies for inducing durable tolerance

The present invention is defined by the claims. In particular, the present invention relates to the use of TCR-deficient CAR-Tregs in combination with anti-TCR complex monoclonal antibodies for inducing durable tolerance.

Keywords: TCR-deficient CAR-Treg - Anti-TCR complex - Stability of CAR-Treg

Patent Application number: European Procedure (Patents) (EPA) - 18 Févr. 2022 - 22 305 182.2

Inventors:

ZUBER JulienCHARBONNIER SoeliBLEIN Tifanie

Publications:

null

Reference:

BIO22067-T1

Inserm Transfert
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Patent filling date: null

Rare disease: No

Second indication: No

Use of tcr-deficient car-tregs in combination with anti-tcr complex monoclonal antibodies for inducing durable tolerance

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