Two rabbits (A and B) were immunized with a mix of two synthetic peptides of murine PTF1a sequence (one N-term peptide, KSFDNIENEPPFEFVS (aa 309-324) […]
The present invention relates to methods and pharmaceutical compositions of inducing immune tolerance by mucosal vaccination with Fc-coupled antigens. […]
Despite the notion that human CD8+ T cells are the final mediators of autoimmune ?-cell destruction in type 1 diabetes (T1D), none of their target […]
Despite the notion that human CD8+ T cells are the final mediators of autoimmune ?- cell destruction in type 1 diabetes (T1D), none of their target […]
GABA is an inducer of ?-to-?-like cell conversion in vivo. This conversion induces ? cell replacement mechanisms through the mobilization of […]
Type 1 diabetes (TID) is an autoimmune disease that results from the selective destruction of insulin-producing ?-cells in pancreatic islets. The […]