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Mouse anti-human hox11l2/tlx3 (clones 34h9 & 10a5)

Mouse monoclonal antibodies recognizing the Hox11L2 gene product.

Interest / Relevance: HOX11L2 (or TLX3) is ectopically expressed in ~20% and ~13% of chidhood or adult T cell acute lymphoblastic leukemia (T-ALL), respectively. HOX11L2 oncogene is therefore considered as a key factor controlling the emergence of some human T-ALL. These monoclonal antibodies represent appropriate tools for exploring the expression and functions of this oncogene as a putative determinant of the onset of these pathologies

Keywords: human T-ALL , oncogene , HOX11L2/TLX3

Scientist's name: Pierre FERRIER
Dominique PAYET-BORNET

Publications:

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Reference:

RT00363

Type of research tool: Antibodies

Uses(1): Academic Research

Uses(2): Proof of concept in vitro

Uses(3): Proof of concept in vivo

Uses(4): Diagnostic

Uses(5): Theranostic (patients stratification, ...)

Inserm Transfert
Research Tools

Clones available: 34H9 (IgG1,kappa)
10A5 (IgG1, kappa)

null

Isotype: null

null

Source: null

null

Specificity: null

Immunogen Seq ID: Peptide conjugates

Cellular Distribution: Nuclear

Know Cross Reactivity: null

Depositor: Dominique PAYET (CIML)

FBS: 10%

Rare disease: No

Last update: 18/06/2024

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