Mouse anti-mouse i-ek (mouse mhc classe ii allodeterminants) (several clones)

A collection of 17 mouse allospecific monoclonal antibodies raised in the A.TH (Is) anti-A.TL (Ik) combination.

Interest / Relevance: These monoclonals identify all the major allotopes of the I-Ek molecule and define several major epitope regions expressed by the alpha and/or beta subuhits of the I-Ek molecule.

Scientist's name: Michel PIERRES
Philippe Naquet

Reference:

RT00339

Type of research tool: Antibodies

Therapy area(1): Immunology

Uses(1): Academic Research

Uses(2): Industry Research (screening, tox.studies, bioreactor, ...)

Type of Product: ...

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Clones available: 40.B, 40.I, 39.I, 9.B, 9.A, 40.E, 39.D, 40.K, 39.G, 40.D, 40.H, 10.B, 10.A, 41.A, 40.C, 40.P, & 7.A

Isotype: lgG2a

Source: Mouse

Some monoclonals cross-react with human MHC class II molecules

Specificity: Some monoclonals cross-react with human MHC class II molecules

Immunogen Seq ID: Spleen cells, thymocytes or Concanavalin-A-activated spleen cells

Know Cross Reactivity: H-2 haplotypes : d,r,v, & b (40.M)
d,p,r,u,v,f , & q (40.I)
d, p, r, u, v, b, & q (9.B & 39I)
d,r,& v (40.E)
d,r,u, & v (39.D)
p,r,u, & v (40.K, 39.G)
d,p,r,u,& v (40.D, 40.H, 10.B, 10.A, 41.A, 40.C , 7.A, & 40.P)
none : 9.A

Depositor: Michel PIERRES

FBS: 10%

Rare disease:

Last update: 14/01/2022

Mouse anti-mouse i-ek (mouse mhc classe ii allodeterminants) (several clones)

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