147

therapeutic
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56

oncology
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310

research tools

46

diagnostic
published patents

Our Technology Offers

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You want access to an innovative offer which is based on the excellence of Inserm, the leading academic research and clinical institute dedicated to human health in Europe? Find out our technologies offers of patents and research tools: here is a sample of our patents.

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Prkcdg510s/g510s mice – preclinical model of lupus

We introduced the Prkcd G510S mutation that we previously associated to a Mendelian cause of SLE in the mouse genome, by means of CRISPR-Cas9 gene […]

Tssp-deficient mice, a model to identify new essential diabetogenic

TSSP is a novel protease suspected to edit the peptide repertoire presented by MHC class II molecules in the thymus. Prss16, the gene coding for TSSP […]

Transgenic mouse model for myotonic dystrophy: dmsxl carrying >1000

This transgenic mice model ("DMSXL") contains large human genomic DNA sequence carrying the DMPK gene with very large repeat (>1200 CTG). […]

Tp53inp1-deficient mouse

This mouse is deficient for TP53INP1 (both isoforms TP53INP1alpha and TP53INP1beta). TP53INP1 is a key stress factor endowed with a tumor suppressor […]

Transgenic mouse model for myotonic dystrophy: dm300 carrying 300 ctg

Transgenic mouse model carrying the myotonic dystrophy type 1 (DM1) locus (45kb of human sequences) with the DMPK gene and about 300 unstable CTG […]

Tailor made high-fat diet fed diabetic mice

We can provide mice a nutritional model of mice which become either type 2 diabetic without obesity, or obese and diabetic or mainly obese. […]

Hu-ucp3 transgenic mice (moderate overexpr.) resistant to high

Uncoupling protein (UCP) 3 is a mitochondrial inner membrane protein expressed predominantly in glycolytic skeletal muscles.Transgenic mice were […]

Scavenger receptor bi knockout mouse

The class B, type I scavenger receptor (Srb1 or Scarb1) is a cell surface HDL receptor. It plays a key role in determining the levels of plasma […]

Microbiota dependent spontaneous colorectal cancer

100% of the animals spontaneously tumor in the distal part of the colon after 7 month of age, or within 5 weeks after bone marrow transfer. The […]

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