Mouse anti-human lat (linker for activation of t cells) (clone lat. 10-17)

- This antibody recognizes the LAT-adaptor protein expressed on T-cells, mast cells and megacaryocytes.- Suitable for use on paraffin sections

Interest / Relevance: - diagnosis of T-cell lymphomas- diagnosis of mastocytosis- useful in the diagnosis of proliferations develop from megacaryocytes
Keywords: null
Scientist's name: Georges DELSOL
Mohamad Talal AL SAATI,Bernard PAYRASTRE
Ragab A Séverin S Gratacap MP Aguado E Malissen M Jandrot-Perrus M Malissen B Ragab-Thomas J Payrastre B.Roles of the C-terminal tyrosine residues of LAT in GPVI-induced platelet activation: insights into the mechanism of PLC gamma 2 activation. Blood. 2007 Oct 1;110(7):2466-74Tedoldi S Paterson JC Hansmann ML Natkunam Y Rüdiger T Angelisova P Du MQ Roberton H Roncador G Sanchez L Pozzobon M Masir N Barry R Pileri S Mason DY Marafioti T Horejsí V.Transmembrane adaptor molecules: a new category of lymphoid-cell markers.Blood. 2006 Jan 1;107(1):213-21



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Clones available: LAT. 10-17
Isotype: null
Source: null
Specificity: null
Immunogen Seq ID: LAT recombinant protein
Cellular Distribution: T-cell, mast cells and megacaryocytes
Know Cross Reactivity: mast cells and megacaryocytes
Depositor: null
FBS: 15%
Rare disease: No
Last update: 18/06/2024

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