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Pharmaceutical compositions for use in the treatment of brain injuries

The invention is in the field of neuroregenerative medicine. Controlling the fate of neural stem cells represents a key therapeutic strategy in […]

Pyk2-based gene therapy gene therapy attenuates cognitive deficits

In the present invention it is shown that the inactivation of the Pyk2 gene does not alter hippocampal development but prevents hippocampal-dependent […]

Pyk2-based gene therapy attenuates cognitive deficits associated to

In the present invention it is shows that the inactivation of the Pyk2 gene does not alter hippocampal development but prevents hippocampal-dependent […]

Ctip fusion to cas9 enhances transgene integration by

The present invention relates to nuclease protein fusions for enhancing genome editing by homology-directed transgene integration (HDI).rnrnThe […]

Increasing tfr1 palmitoylation as a novel therapeutic strategy for

The present invention relates to methods and pharmaceutical compositions for the treatment of neurodegeneration with brain iron accumulation (NBIA). […]

Methods and compositions for the preservation of organs

The present invention relates to methods and compositions for the preservation of organs.rnrnIn particular, the present invention relates to an […]

Plga microparticles loaded with a fluoroquinolone forthe treatment of

This invention relates to:rn- PLGA (poly lactic-co-glycolic acid, i.e. a copolymer of poly lactic acid (PLA) and poly glycolic acid) microparticles […]

Direct pulmonary delivery of oseltamivir carboxylate for the treatment

The present application relates to antiviral compounds and to their use for the treatment and/or prevention of viral infections.rnMore particularly, […]

Product combination for the treatment of filovirus infections

The present invention relates to methods and pharmaceutical compositions for the treatment of filovirus infections. Although several antivirals have […]

A progression model that estimates a normative scenario of the

The invention relates to age-related brain diseases, such as Parkinson’s or Alzheimer’s disease. Statistical models based on the regression of […]