Direct pulmonary delivery of oseltamivir carboxylate for the treatment of influenza infections

The present application relates to antiviral compounds and to their use for the treatment and/or prevention of viral infections. More particularly, the present invention relates to Sulconazole and Sulconazole derivatives for their use in treating and/or preventing viral infections. Sulconazole and its derivatives demonstrated an effective anti-adenoviral activity used at 5 µM in-vitro. Moreover, these compounds demonstrated an increased activity compared to the lead compound Cidofovir (standard clinical drug used against adenovirus infection).

Keywords: Infectious diseases, antivirals,pulmonary formulation
Patent Application number: EP16305605.4
Inventors:
Sandrine MARCHANDWilliam COUET
Publications:
J Control Release. 2018 Feb 10;271:118-126. doi: 10.1016/j.jconrel.2017.12.021. Epub 2017 Dec 22.

Reference:

BIO16197-T1

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Patent filling date: 25-05-2016

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