Intestinal cathelicidin antimicrobial peptide shapes the gut

The present invention relates to the treatment of autoimmune diseases. The inventors determined that the cathelicidin related antimicrobial peptide […]

Fc-engineered anti-human ige antibodies and methods of use

The present invention relates to the treatment of IgE-mediated disease. The inventors hypothesized that formation of immune complexes between […]

Novel b-raf inhibitors devoid of rapid metabolism and of binding to

The present invention relates to N-(3-(5-(pyrimidin-4-yl)thiazol-4-yl)phenylsulfonamide compounds which are useful as inhibitors of protein kinases, […]

Mesenchymal stem cell derived extracellular vesicles loaded with at

Several gastrointestinal and gynecological malignancies have the potential to disseminate and grow in the peritoneal cavity. The occurrence of […]

Targeting the secreted ige poly-a signal allows specific inhibition of

Immunoglobulins (Ig) are expressed either on the surface of B cells or as secreted antibodies by plasma cells that represents the final stage of B […]

New method to treat acidosis related diseases

The present invention relates to the treatment of acidosis related diseases. In this study, the inventors have investigated how human monocytes adapt, […]

Methods for improving relaxation of striated myocytes

The Inventors developed conditions allowing to efficiently detect differences in cardiomyocytes relaxation phases associated with increased […]

Methods and pharmaceutical compositions for inducing immune tolerance

The present invention relates to methods and pharmaceutical compositions of inducing immune tolerance by mucosal vaccination with Fc-coupled antigens. […]

Methods and compositions for treating skin afflictions

The present invention relates to a method for treating skin afflictions in a subject comprising a step of administering said subject with a […]