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Ualh cell line

UALH were generated by transfection of osteocarcinoma cancer U2OS cells with the (ARE-RAD9)6-collagenase-Luciferase-SV40-hygromycin plasmid. rnThe plasmid (ARE RAD9)6-Coll-Luc-SVNeo contains a luciferase gene driven by the mouse mammary tumor virus promoter and a neomycin phosphotransferase gene under the control of SV40 promoter. rn

Interest / Relevance: These cells are a negative control cell line for measurement of nuclear receptor activity.

Keywords: Luciferase, pharmaceutical and environmental androgens

Scientist's name: Patrick BALAGUER
Patrick Balaguer

Publications:

Dellal H Boulahtouf A Alaterre E Cuenant A Grimaldi M Bourguet W Gongora C Balaguer P* Pourquier P.* High content screening using new U2OS reporter cell models identifies harmol hydrochloride as a selective and competitive antagonist of the androgen receptor. Cells 2020 9: 1469.

Reference:

RT00624

Type of research tool: Cell Lines

Uses(1): Industry Research (screening, tox.studies, bioreactor, ...)

Inserm Transfert
Research Tools

Organism: null

Tissue: null

Morphology: null

Passage Number: null

Subculture Routine: null

Culture Medium: null

Growth Properties: null

Karyotype: null

Rare disease: No

Last update: 12/06/2024

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