Back to results

Rat mesothelial cell line m2-2

Transformed rat mesothelial cell line isolated from the peritoneal fluid of a male rat (Fischer F344) after 270 days of induction with crocidolite (blue asbestos) injected intraperitoneously.

Interest / Relevance: - Academic Research: identification of markers of neoplastic / transformed mesothelial cells, analyses of chromosomal damage induced by asbestos, studies of the mechanism of asbestos-induced oncogenesis, implication of fibrosis and inflammation.rn- Industry research: antibody production, screening of new anticancer agents, identification of factors that increase mesothelial proliferation and migration. rn- Therapeutic: development of epigenetic drugs, design of cancer vaccines, regenerative medicine applications.rnCellular and Molecular Biology, Immunology.

Keywords: mesothelial cells , tumor marker , tumor invasion process , malignant transformation , proliferation rate

Scientist's name: Daniel POULIQUEN

Publications:

null

Reference:

RT00426

Type of research tool: Cell Lines

Therapy area(1): Infectious Diseases

Therapy area(2): Oncology

Therapy area(3): Others

Uses(1): Academic Research

Uses(2): Proof of concept in vitro

Uses(3): Industry Research (screening, tox.studies, bioreactor, ...)

Uses(4): Diagnostic

Uses(5): Therapeutic

Inserm Transfert
Research Tools

Organism: Rat

Tissue: Mesothelium (peritoneal cavity)

Morphology: Sarcomatoid

Passage Number: 4, 5

Subculture Routine: null

Culture Medium: RPMI 1640 supplemented with 10% FCS and 2mM L-Glutamine

Growth Properties: In 6-well plates (300,000 cells/well): Doubling time: 24-48h. Saturation density: 100,000-200,000 cells / sq-cm.

Karyotype: under investigation

Rare disease: No

Last update: 12/06/2024

You might also be interested in

RT00626

Uses: Industry Research (screening, tox.studies, bioreactor, ...)

Therapy Area: Oncology

Type of research tool: Cell Lines

Ug5ln gal4-hmr cell line

UG5LN were generated by transfection of osteocarcinoma cancer U2OS cells with the […]

RT00625

Uses: Industry Research (screening, tox.studies, bioreactor, ...)

Therapy Area: Oncology

Type of research tool: Cell Lines

Ug5ln cell line

UG5LN were generated by transfection of osteocarcinoma cancer U20S cells with the […]

RT00624

Uses: Industry Research (screening, tox.studies, bioreactor, ...)

Therapy Area: Oncology

Type of research tool: Cell Lines

Ualh cell line

UALH were generated by transfection of osteocarcinoma cancer U2OS cells with the […]

RT00586

Uses: Industry Research (screening, tox.studies, bioreactor, ...)

Therapy Area: Oncology

Type of research tool: Cell Lines

Ualh har cell line

UALH were generated by transfection of osteocarcinoma cancer U2OS cells with the […]

RT00582

Uses: Industry Research (screening, tox.studies, bioreactor, ...)

Therapy Area: Oncology

Type of research tool: Cell Lines

Palm cell line

PALM were generated by co-transfection of cervical cancer PC3 cells with the […]

RT00583

Uses: Industry Research (screening, tox.studies, bioreactor, ...)

Therapy Area: Oncology

Type of research tool: Cell Lines

Meln (her alpha) cell line

MELN were generated by transfection of breasr cancer MCF-7 cells with the […]

RT00623

Uses: Industry Research (screening, tox.studies, bioreactor, ...)

Therapy Area: Oncology

Type of research tool: Cell Lines

Hrln (hrar alpha) cell line

HRLN were generated by transfection of cervical cancer HeLa cells with the […]

RT00622

Uses: Industry Research (screening, tox.studies, bioreactor, ...)

Therapy Area: Oncology

Type of research tool: Cell Lines

Hmln (hgr) reporter cell line

HMLN were generated by transfection of cervical cancer HeLa cells with the MMTV- […]

RT00558

Uses: Industry Research (screening, tox.studies, bioreactor, ...)

Therapy Area: Oncology

Type of research tool: Cell Lines

Hg5ln gal4-hppar alpha cell line

HG5LN were generated by transfection of cervical cancer HeLa cells with the […]

RT00559

Uses: Industry Research (screening, tox.studies, bioreactor, ...)

Therapy Area: Oncology

Type of research tool: Cell Lines

Hg5ln gal4-hppar gamma cell line

HG5LN were generated by transfection of cervical cancer HeLa cells with the […]

RT00569

Uses: Industry Research (screening, tox.studies, bioreactor, ...)

Therapy Area: Oncology

Type of research tool: Cell Lines

Hg5ln gal4-hppar beta/delta cell line

HG5LN were generated by transfection of cervical cancer HeLa cells with the […]

RT00585

Uses: Industry Research (screening, tox.studies, bioreactor, ...)

Therapy Area: Oncology

Type of research tool: Cell Lines

Hg5ln rtr alpha cell line

HG5LN were generated by transfection of cervical cancer HeLa cells with the […]