The present invention relates to polypeptide for engineering integrase chimeric proteins and their use in gene therapy. rnA key challenge for gene […]
The invention related to metabolically stable Apelin analogs and their use for the prevention or the treatment of diseases mediated by the apelin […]
The present invention relates to an anti-Notch 3 antibody therapy useful for treatment of patients with cerebral autosomal dominant arteriopathy with […]
Tuberculosis (TB), caused by M. tuberculosis infection, continues to be one of the most prevalent infectious diseases worldwide. The WHO has also […]
The present invention relates to a method for the intercellular transfer of an amount of mitochondria isolated from a population of donor cells into a […]
The present invention relates to a method of treating Alzheimer’s disease by administration to the subject of a therapeutically effective amount of […]
The invention relates to two isolated human neutralizing antibodies that binds to an undisclosed Tyrosine Kinase Receptor, which further induces […]
The present invention relates to an anti-NMDA antibody or fragment or derivative thereof which is effective in inhibiting the deleterious effects of […]
The inventors show that apelin plays a role in energy metabolism and particularly in energetic mechanisms in mitochondria. rnThey show that apelin […]
The present invention relates to the use of an optimized truncated flagellin (TLR5 agonist devoided of toxic effect) for preventing or treating […]