Inflammation is a prominent feature of ischemia-reperfusion injury (IRI) characterized by leukocyte infiltration and renal tubular injury. However, […]

The severity of renal lesions after nephron reduction varied substantially among mouse strains and required activation of EGFR. Lipocalin 2 (Lcn2, […]

The present invention relates to a method for treating a subject suffering from a liver disease comprising a step of administering said subject with a […]

The mechanisms driving the development of extracapillary lesions in focal segmental glomerulosclerosis (FSGS) and crescentic glomerulonephritis (CGN) […]

GABA is an inducer of ?-to-?-like cell conversion in vivo. This conversion induces ? cell replacement mechanisms through the mobilization of […]

The present invention relates to a method for modulating blood-brain barrier (BBB) in a subject comprising a step of administering said subject with a […]

The present invention relates to a method for treating a subject suffering from melanoma resistant by administering to said subject an inhibitor of […]

The adult mammalian heart regeneration is largely prevented by the limited proliferative capacity of the resident cardiomyocytes (CMs). Here, the […]

Inventors have found that the MT mutation puts an alternative start codon in frame which leads to the translation of a second TRESK fragment. […]

The present invention relates to methods and pharmaceutical compositions for the treatment of age-related cardiometabolic diseases. In particular, the […]