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A checkpoint kinase 1 inhibitor sensitises cancer cells to

The present invention relates to the field of cancer treatment. In this study, the inventors sought to investigate whether this antiproliferative […]

Lipopeptide compound for the treatment of pain disorder

The invention is based on the discovery of a new bacterial compound with analgesic properties which could be used as a new tool for the treatment of […]

Pyk2-based gene therapy gene therapy attenuates cognitive deficits

In the present invention it is shown that the inactivation of the Pyk2 gene does not alter hippocampal development but prevents hippocampal-dependent […]

Pyk2-based gene therapy attenuates cognitive deficits associated to

In the present invention it is shows that the inactivation of the Pyk2 gene does not alter hippocampal development but prevents hippocampal-dependent […]

Novel target and mab candidates for the treatment of hcmv infection

The present invention relates to a method for treating an infection, particularly HCMV infection. To date, there are very few reports on the role of […]

Allele-specific silencing therapy for dynamin 2-related diseases

The invention relates to an allele specific siRNA able to silence the expression of only one allele of a heterozygous DNM2 gene, for treating diseases […]

Apelin receptor agonist for the treatment of post-operative cognitive

The present invention relates to methods and pharmaceutical compositions for the treatment of post-operative cognitive dysfunction. In particular, the […]

Factor h fragment for use as an anti-angiogenic agent

The invention relates to a complement factor H fragment for use in the therapy and/or prophylaxis of a disease involving neovascularization.rnPOC in […]

Methods for expanding a population of alveolar macrophages in a long

The present invention relates to methods for expanding a population of alveolar macrophages in a long term culture. In particular, an object of the […]

G quadruplex ligands to treat infectious diseases

The present inventions relate to rn- metallated porphyrin derivatives as ligands of G quadruplex and their use as anti-viral agents. Porphyrin […]