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In vitro tests allowing to identify the potential for mdm2 inhibitors

TP53 mutations are the most frequent mutations in all cancer subtypes and their acquisition are key events leading to the transformation of chronic […]

New method to evaluate pancreatic prognosis

The present invention relates to the prediction of the survival time of a patient suffering of a pancreatic cancer. In this study, the inventors aimed […]

Methods for the diagnosis and treatment of t cell-lymphomas ccr8

T-cell lymphomas are a heterogeneous group of malignancies involving T lymphocytes and generally characterized by a poor prognosis. Among them, […]

Methods of determining whether a patient suffering froma

Pheochromocytomas produce and store catecholamines. The release of excessive amounts of catecholamine can lead to life-threatening […]

Bile salts bactosensor and use thereof for diagnostic and therapeutic

Bile salts are steroid acids derived from cholesterol in the liver, are released into the gastrointestinal tract to aid in digestion and are […]

Methods of assessing the risk of developing progressivemultifocal

Natalizumab a monoclonal antibody is associated with the risk of progressive multifocal leukoencephalopathy (PML), an infection caused by the John […]

New method to evaluate cancer prognosis

The present invention relates to the prediction and treatment of cancers. In this study, the inventors analyzed how invalidation of the mitochondrial […]

Use of alarmins as biomarkers for assessing ischemiareperfusion injury

The inventors aim to assess IL-33 and HMGB1 contributions as alarmins to I/R injury following solid organ transplantation in particular liver […]

Blocking caspase and/or fasl for preventing fataloutcome in covid-19

Herein the inventors demonstrated that CD4 and CD8 T cells from COVID-19 patients are more prone to undergo death and that blocking caspase activation […]

Methods and compositions for detecting the activation of mtor pathway

The present invention relates to a method for measuring the activation of mTOR pathway in a subject suffering from a kidney disease associated with a […]