Immunoglobulins (Ig) are expressed either on the surface of B cells or as secreted antibodies by plasma cells that represents the final stage of B […]
The Inventors developed conditions allowing to efficiently detect differences in cardiomyocytes relaxation phases associated with increased […]
The present invention concerns an oligonucleotide modified by substitution at the 3’ or the 5’ end by at least triple alkyl chain or at least one […]
Worldwide, 1% to 2% of the general adult population have heart failure (HF), which is accompanied by reduced quality of life, high morbidity, […]
The invention is based on the discovery of a new bacterial compound with analgesic properties which could be used as a new tool for the treatment of […]
The invention relates to an allele specific siRNA able to silence the expression of only one allele of a heterozygous DNM2 gene, for treating diseases […]
The invention relates to a complement factor H fragment for use in the therapy and/or prophylaxis of a disease involving neovascularization.rnPOC in […]
The present invention relates to methods for expanding a population of alveolar macrophages in a long term culture. In particular, an object of the […]
The present invention concerns lentiviral vectors enabling the expression of membrane-anchored and secreted antibodies by B cells. This invention […]
The invention related to metabolically stable Apelin analogs and their use for the prevention or the treatment of diseases mediated by the apelin […]