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Use of agents capable of inducing lc3-associated phagocytosis for

Sustained hepatic and systemic inflammation, in particular originating from monocyte/macrophages, is a driving force for chronic liver disease […]

Selective pharmacological inhibition of epac1 for the treatment of

The present invention relates to the treatment of idiopathic pulmonary fibrosis. Today, there is no cure for IPF. The inventors showed that EPAC1 […]

Ngal as a novel target for the treatment of chronic kidney disease

The severity of renal lesions after nephron reduction varied substantially among mouse strains and required activation of EGFR. Lipocalin 2 (Lcn2, […]

Monoacylglycerol lipase as target for the treatment of liver fibrosis

The present invention relates to methods and pharmaceutical compositions for the treatment of fibrosis. In particular, the present invention relates […]

Methods and pharmaceutical compositions for the treatment of

The present invention relates to methods and pharmaceutical compositions for the treatment of age-related cardiometabolic diseases. In particular, the […]

Periostin inhibitor in the prevention or treatment of chronic kidney

The present invention relates to an agent which binds to periostin selected from the group consisting of antibodies, aptamers, small organic molecules […]