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Ppar-gamma agonist as target for the treatment of rapidly progressive

This study demonstrates the pivotal role of the local PPAR-gamma agonist system in maintaining podocyte quiescence and orchestrating the global […]

Cdc25a phosphatase inhibitor for use in thetreatment of a drug

The invention relates to a CDC25A phosphatase inhibitor for use in the treatment of drug resistant cancer or for use in the prevention of tumor […]

Anti notch3 antibody for cadasil treatment

The present invention relates to an anti-Notch 3 antibody therapy useful for treatment of patients with cerebral autosomal dominant arteriopathy with […]

Mitoception: novel method for the intracellular transfer of isolated

The present invention relates to a method for the intercellular transfer of an amount of mitochondria isolated from a population of donor cells into a […]

Lipid antisens oligonucleotide targeting fxyd2 as a therapeutic agent

The present invention relates to an inhibitor of FXYD2 gene expression for use in a method for treating neuropathic pain in a patient in need thereof. […]

Soluble apps?-based gene therapy in alzheimer’s disease

The present invention relates to a method of treating Alzheimer’s disease by administration to the subject of a therapeutically effective amount of […]

Nanoparticle based glue, biocompatible sealant for surgery

The present invention relates to methods for adhering tissue surfaces and materials and biomedical uses thereof. In particular the present invention […]

Anti-kit mab for the treatment of cancer (aml, gist)

The invention relates to two isolated human neutralizing antibodies that binds to an undisclosed Tyrosine Kinase Receptor, which further induces […]

Neuroglobin gene therapy for use in the treatment or prevention of a

Mitochondrial dysfunction is responsible for hereditary optic neuropathies. We wished to determine whether preserving mitochondrial […]

Antibody protecting from bscb leakage induced cns damages

The present invention relates to an anti-NMDA antibody or fragment or derivative thereof which is effective in inhibiting the deleterious effects of […]