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Ex vivo gene therapy based vaccine with nucleic acid molecule encoding

The present invention relates to a method of treating a B-cell malignancy in a subject using a vaccine composition comprising a population of […]

A microrna switch regulates the rise in hypothalamic gnrh production

A method for diagnosing a reproduction-related disorder in an individual, comprising:rna) measuring the level of a miR200 nucleic acid and/or miR155 […]

Modulator of wip1 levels to treat wolfram syndrome

The present invention relates to novel therapeutic ways for treating Wolfram Syndrome (WS) by targeting the neuronal calcium sensor 1 (NCS1). The […]

Apelin receptor agonist for the treatment of post-operative cognitive

The present invention relates to methods and pharmaceutical compositions for the treatment of post-operative cognitive dysfunction. In particular, the […]

Reduction of carcinomatosis risk using icodextrin as a carrier

The present invention relates to methods and pharmaceutical compositions for the prophylactic treatment of peritoneal carcinomatosis. In particular, […]

Factor h fragment for use as an anti-angiogenic agent

The invention relates to a complement factor H fragment for use in the therapy and/or prophylaxis of a disease involving neovascularization.rnPOC in […]

Methods for expanding a population of alveolar macrophages in a long

The present invention relates to methods for expanding a population of alveolar macrophages in a long term culture. In particular, an object of the […]

Method for the treatment of disease associated with angiogenesis

The present invention relates to a method of treating disease associated with angiogenesis using an N-Methyl-D-aspartate receptor (NMDA) antagonist. […]

G quadruplex ligands to treat infectious diseases

The present inventions relate to rn- metallated porphyrin derivatives as ligands of G quadruplex and their use as anti-viral agents. Porphyrin […]

Nanoblade technology: high efficiency delivery of crisprs components

The present invention relates to a virus-derived particle comprising one or more Cas protein(s), as well as to kits and methods using the same for […]