Anti notch3 antibody for cadasil treatment

The present invention relates to an anti-Notch 3 antibody therapy useful for treatment of patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.

Keywords: Neurology - Neurovascular -CADASIL - monoclonal antibody
Patent Application number: EP20150780771
Inventors:
Anne JOUTEL
Publications:
Brain. 2013 Jun;136(Pt 6):1830-45. doi: 10.1093/brain/awt092. Epub 2013 May 6. Ann Neurol. 2016 Mar;79(3):387-403. doi: 10.1002/ana.24573. Epub 2016 Feb 10.

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