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Methods and compositions for treating cell senescence accumulation

The inventors have surprisingly demonstrated that GD3 positive senescent cells inhibit NK cell in vitro and in vivo while GD3 negative senescent cells […]

Use of antagonists of th17 cytokines for the treatment of bronchial

Bronchial remodelling is a prominent feature of severe asthma and a potential therapeutic target. Some data indicate that Th17 cytokines in particular […]

Method for treating t- helper type 2 mediated disease

The present invention relates to the treatment of T- helper type 2 (Th2)-mediated disease. Here, the inventors set out to investigate at the genome […]

Antibodies specific for il20-rb and uses thereof for the treatment of

Chronic obstructive pulmonary disease (COPD) remains a major cause of morbidity and mortality worldwide. Acute exacerbation of COPD (AE-COPD) in […]

Selective pharmacological inhibition of epac1 for the treatment of

The present invention relates to the treatment of idiopathic pulmonary fibrosis. Today, there is no cure for IPF. The inventors showed that EPAC1 […]

Methods and compositions for treating cell senescence accumulation

The inventors have surprisingly demonstrated that GD3 positive senescent cells inhibit NK cell in vitro and in vivo while GD3 negative senescent cells […]

Methods for predincting the risk of developing pulmonary

The present invention relates to methods for predicting the risk of developing pulmonary colonization/infection by P. aeruginosa. The inventors […]

Cellular fibronectin toolset

Expression vectors encoding human 'cellular' fibronectin variants harboring the alternatively spliced Extra Domains B and/or A (or neither) ; […]

Methods and composition for the treatment of allergic asthma

The present invention relates to a method of treating allergic asthma in a subject in need thereof comprising a step of administering to said subject […]