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Use of slamf1 as a biomarker in colorectal cancer

Innate lymphoid cells (ILCs) are tissue-resident lymphocytes that differ from conventional T lymphocytes in having no antigen-specific receptors. ILCs […]

Human monoclonal antibodies against orexin receptor type 1

The present invention relates to human monoclonal antibodies against orexin receptor type 1 (OX1R) and uses thereof for the treatment of cancer. […]

Microbiota dependent spontaneous colorectal cancer

100% of the animals spontaneously tumor in the distal part of the colon after 7 month of age, or within 5 weeks after bone marrow transfer. The […]

Compounds targeting hsp110 protein for cancer treatment

HSP110 is involved in multiple tumorigenic processes, but no inhibitor was known to date. The inventors have identified for the first time HSP110 […]

Enhancement of 5-fluorouracil cytotoxicity by pyridoxal 5’-phosphate

The invention relates to methods and pharmaceutical compositions for treating cancer in a subject in need thereof. The inventors thought that low […]