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Methods and compositions for treating cell senescence accumulation

The inventors have surprisingly demonstrated that GD3 positive senescent cells inhibit NK cell in vitro and in vivo while GD3 negative senescent cells […]

Methods for prognosis, stratification and monitoring of the severity

In the present invention inventors used measured cytokine levels in serum of patients with COVID-19, at the time of hospital admission. Thereafter, […]

Methods for the diagnosis and treatment of t cell-lymphomas ccr8

T-cell lymphomas are a heterogeneous group of malignancies involving T lymphocytes and generally characterized by a poor prognosis. Among them, […]

Method for pronosis and treating a patient suffering from cancer

Complement components form a plasma innate immune cascade but could also serve as multitasking proteins, as they have functions beyond this system. […]

Bile salts bactosensor and use thereof for diagnostic and therapeutic

Bile salts are steroid acids derived from cholesterol in the liver, are released into the gastrointestinal tract to aid in digestion and are […]

Use of alarmins as biomarkers for assessing ischemiareperfusion injury

The inventors aim to assess IL-33 and HMGB1 contributions as alarmins to I/R injury following solid organ transplantation in particular liver […]

Blocking caspase and/or fasl for preventing fataloutcome in covid-19

Herein the inventors demonstrated that CD4 and CD8 T cells from COVID-19 patients are more prone to undergo death and that blocking caspase activation […]

Methods and compositions for detecting the activation of mtor pathway

The present invention relates to a method for measuring the activation of mTOR pathway in a subject suffering from a kidney disease associated with a […]

Use of mait cells as biomarkers and biotargets in covid-19

Immune system dysfunction is paramount in Coronavirus disease 2019 (COVID-19) severity and fatality rate. Mucosal-Associated Invariant T (MAIT) cells […]

Gdf3 as biomarker and biotarget in post-ischemic cardiac remodeling

Markers of an intense scarring process in the early phase post- myocardial infarction (MI) are still undetermined, and the identification of patients […]