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Triarylpyridine compounds and use thereof for treating cancer

The invention relates to new bis-triazole 2,4,6-triarylpyridines compounds and their use in the field of oncology, in particular in the prevention […]

Gene therapy coding for anti-tau nanobody to treat rare tauopathies

The invention relates to generation, optimization and characterisation of VHH targeted against Tau MTBD (microtubule-binding domain) with high […]

Enhancement of 5-fluorouracil cytotoxicity by pyridoxal 5’-phosphate

The invention relates to methods and pharmaceutical compositions for treating cancer in a subject in need thereof. The inventors thought that low […]

Ctip fusion to cas9 enhances transgene integration by

The present invention relates to nuclease protein fusions for enhancing genome editing by homology-directed transgene integration (HDI). The […]

G quadruplex ligands to treat infectious diseases

The present inventions relate to - metallated porphyrin derivatives as ligands of G quadruplex and their use as anti-viral agents. Porphyrin […]