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Mouse anti-mouse i-ek (mouse mhc classe ii allodeterminants) (several clones)
A collection of 17 mouse allospecific monoclonal antibodies raised in the A.TH (Is) anti-A.TL (Ik) combination.
Interest / Relevance:
These monoclonals identify all the major allotopes of the I-Ek molecule and define several major epitope regions expressed by the alpha and/or beta subuhits of the I-Ek molecule.
Scientist's name:
Michel PIERRES
Philippe Naquet
Reference:
RT00339
Type of research tool:
Antibodies
Therapy area(1):
Immunology
Uses(1):
Academic Research
Uses(2):
Industry Research (screening, tox.studies, bioreactor, ...)
Type of Product:
...
Business Developper
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Inserm Transfert
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Clones available:
40.B, 40.I, 39.I, 9.B, 9.A, 40.E, 39.D, 40.K, 39.G, 40.D, 40.H, 10.B, 10.A, 41.A, 40.C, 40.P, & 7.A
Isotype:
lgG2a
Source:
Mouse
Some monoclonals cross-react with human MHC class II molecules
Specificity:
Some monoclonals cross-react with human MHC class II molecules
Immunogen Seq ID:
Spleen cells, thymocytes or Concanavalin-A-activated spleen cells
Know Cross Reactivity:
H-2 haplotypes : d,r,v, & b (40.M)
d,p,r,u,v,f , & q (40.I)
d, p, r, u, v, b, & q (9.B & 39I)
d,r,& v (40.E)
d,r,u, & v (39.D)
p,r,u, & v (40.K, 39.G)
d,p,r,u,& v (40.D, 40.H, 10.B, 10.A, 41.A, 40.C , 7.A, & 40.P)
none : 9.A
Depositor:
Michel PIERRES
FBS:
10%
Rare disease:
Last update:
14/01/2022
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