Mouse anti-mouse & anti-rat cd90.1 (mouse thy-1.1) (clone h171-146)

Monoclonal antibody raised in (A.TLxA.TH)F1 hybrid mouse (expressing the Thy-1b allele) immunized with T hybridoma cells [derived from BALB/c T cells (Thy-1b allele) fused with the BW5147 AKR thymoma (Thy-1a allele)].

Interest / Relevance: The Thy-1.1 monoclonal antibody binds to a Thy-1.1 determinant expressed in Thy-1a mouse (e.g. AKR thymocytes) or T hybridoma cells derived from BW5147 AKR thymoma cells)and in rat thymocytes. This monoclonal antibody activates both mouse and rat T cells to proliferate or produce IL-2.
Keywords: Thy-1.1 , Mouse & rat , activating MAb
Scientist's name: Philippe NAQUET
Michel PIERRES
Publications:
Pont S. et al. A Thy-1.1-specific monoclonal alloantibody activates both mouse and rat T cells. Cellular Immunology (1987) 107 : 64-73

Reference:

RT00352

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Clones available: H171-146
IgG3
Isotype: IgG3
null
Source: null
Mouse (Thy-1b) and rat
Specificity: Mouse (Thy-1b) and rat
Immunogen Seq ID: Mouse T cell hybridoma
Cellular Distribution: null
Know Cross Reactivity: null
Depositor: Michel PIERRES
FBS: 10%
Rare disease: No
Last update: 12/06/2024

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