Mouse anti-human melanoma associated antigen (clone kba.62)

- Anti-melanoma associated antigen reactive on paraffin sections.- KBA.62 is useful in ascertaining the immunomorphological diagnosis of malignant melanoma in routinely processed paraffin sections.- Staining is localised predominantly to the cell membrane with little or no cytoplasmic reactivity. Negative staining is observed in the majority of human non-melanocytic neoplasms.

Interest / Relevance: - Immunohistochemical diagnosis of primary and mmelanome.- Detection of melanoma cells in the sentinel lymph node.- KBA.62 reacts strongly and uniformly with the majority of benign and malignant melanocytic proliferations. KBA.62 antibody is a useful additional marker for melanoma, specifically in desmoplastic/spindle cell cases.
Keywords: null
Scientist's name: Georges DELSOL
Mohamad Talal AL SAATI
Publications:
- Production and characterisation of an antimelanoma monoclonal antibody KBA.62 using a new melanoma cell line reactive on paraffin wax embedded sections. Cohen-Knafo E al Saati T Aziza J Ralfkiaer E Selves J Gorguet B Delsol G. J Clin Pathol. 1995 Sep;48(9):826-31.- KBA.62: a useful marker for primary and metastatic melanomasPagès C Rochaix P al Saati T Valmary-Degano S Boulinguez S Launay F Carle P Lauwers F Payoux P Le Guellec S Brousset P Lamant L.Hum Pathol. 2008 Aug;39(8):1136-42. Epub 2008 May 20

Reference:

RT00385

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Clones available: KBA.62
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Isotype: null
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Source: null
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Specificity: null
Immunogen Seq ID: KAL human melanoma cell line
Cellular Distribution: null
Know Cross Reactivity: endothelial cells
Depositor: null
FBS: 15%
Rare disease: No
Last update: 18/06/2024

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