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Garp as a biomarker and biotarget in t-cell malignancies

The present study of the regulatory T phenotype of Sézary cells led to the discovery of the expression of GARP (LRRC32) by Sézary cells. GARP has […]

Methods for the diagnosis and treatment of acute lymphoblastic

The present invention relates to a method of treating acute lymphoblastic leukemia in a patient in need thereof comprising administering to the […]

Lrrc33 as a biomarker and biotarget in cutaneous t-cell lymphomas

The present study of the regulatory T phenotype of Sézary cells led to the discovery of the expression of LRRC33 by Sézary cells. LRRC33 therefore […]

Methods and composition to identify and treat subjects resisting to

The present invention relates to a method for treating a subject suffering from a cancer comprising a step of administering said subject with a […]

Cd38 as a biomarker and biotarget in cell-lymphomas

T-cell lymphomas are a heterogeneous group of malignancies involving T lymphocytes and generally characterized by a poor prognosis. Among them, […]

Methods and compositions for treating triple negative breast cancer

Inventors analyzed the prognostic value of tumor and stromal-derived SPARC in a large series that included 148 non-metastatic TNBC patients with a […]

Method for diagnosing colorectal cancer

The present invention relates to the diagnosing of colorectal cancer. The inventors have thus designed an efficient, rapid and cost-effective method […]

Methods for improving the efficacy of hdac inhibitor therapy and

Investigating the impact of Tau protein expression in cancer cell lines, Inventors have demonstrated that the Tau expression is associated with an […]

Early and non-invasive method for assessing a subject’s risk of

In the present invention inventors perform studies on extracellular vesicles isolated from urine samples to assess the biomarker potential of measures […]