Ssbp1 as a new target, and biomarker for predicting risk of ocular

Inventors report heterozygous mutations in mitochondrial single-stranded DNA-binding protein SSBP1 in multiple unrelated families with non-syndromic […]

Rock inhibitors to treat diabetic retinopathy

In diabetic retinopathy, the exact mechanisms leading to retinal capillary closure and to retinal barriers breakdown remain imperfectly understood. […]

Use of fzd7 inhibitors for the treatment of retinal neovascularization

Retinal ischemia and abnormal blood vessels growth are major determinants in the pathogenesis of retinopathy of prematurity (ROP) and proliferative […]

Modulator of wip1 levels to treat wolfram syndrome

The present invention relates to novel therapeutic ways for treating Wolfram Syndrome (WS) by targeting the neuronal calcium sensor 1 (NCS1). The […]

Factor h fragment for use as an anti-angiogenic agent

The invention relates to a complement factor H fragment for use in the therapy and/or prophylaxis of a disease involving neovascularization.rnPOC in […]

Neuroglobin gene therapy for use in the treatment or prevention of a

Mitochondrial dysfunction is responsible for hereditary optic neuropathies. We wished to determine whether preserving mitochondrial […]