The present invention relates to the diagnosis of gastrointestinal stromal tumors (GISTs). The present invention also relates to methods and […]

The present invention relates to human monoclonal antibodies against orexin receptor type 1 (OX1R) and uses thereof for the treatment of cancer. […]

The present invention relates to method and composition for treating melanoma. The inventors have shown that a decrease in LYN expression, in melanoma […]

Immune checkpoint blockade therapy is based on the inhibition of the tumor-mediated suppression of anticancer immune responses. However, the efficacy […]

The present invention relates to methods for enhancing the potency of the immune checkpoint inhibitors. In particular, the present invention relates […]

The response of subjects suffering from cancer to MAPK inhibitors is dramatically impaired by secondary resistances and rapid relapse. So far, the […]

The present invention relates to a method and composition for treating melanoma. More particularly, inventors have shown that high expression of USP14 […]

The invention relates to methods for predicting the outcome of a patient suffering from prostate cancer and methods for the treatment of prostate […]

Immune checkpoint inhibitors (ICI) have revolutionized therapy for advanced cancer, however many patients still do not respond to treatment. However, […]

The present invention relates to use of soluble CD27 as a biomarker to predict the reponse to an immune checkpoint inhibitor treatment. Inventors have […]