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Methods for the diagnosis and treatment of acute lymphoblastic

The present invention relates to a method of treating acute lymphoblastic leukemia in a patient in need thereof comprising administering to the […]

Use of cd160 as a biomarker in acute myeloid leukemia

Natural killer (NK) cells are innate cytotoxic lymphoid cells (ILCs) involved in the killing of infected and tumor cells. Several NK cell subsets have […]

Methods for discontinuing a treatment with a tyrosinekinase inhibitor

The present invention relates to a method for discontinuing a treatment with a TKI by determining the number and/or frequency of innate CD8(+) T-cells […]

Method of treatment and pronostic of acute myeloid leukemia

The present invention relates to the treatment of AML. The inventors previously discovered a new epigenetic biomarker in a cohort of CN-AML patients; […]

Methods of determining whether patients suffering from acute myeloid

Deciphering the impact of metabolic intervention on response to anticancer therapy represents a path toward improved clinical responses. Here, the […]

Retinoic acid and arsenic trioxide trigger degradation of mutated

The present invention relates to methods and pharmaceutical compositions for the treatment of acute myeloid leukemia. In particular, the present […]

Targeting myeloperoxidase overcomes cytarabine resistance in human

Chemotherapy commonly alters cellular redox balance and increases the oxidative state. Recent studies have reported that chemoresistant cells have an […]

Cdc25a phosphatase inhibitor for use in thetreatment of a drug

The invention relates to a CDC25A phosphatase inhibitor for use in the treatment of drug resistant cancer or for use in the prevention of tumor […]