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Gdf3 as biomarker and biotarget in post-ischemic cardiac remodeling

Markers of an intense scarring process in the early phase post- myocardial infarction (MI) are still undetermined, and the identification of patients […]

Use of mast cell stabilizer for the treatment of heart failure with

Heart failure with preserved ejection fraction (HFpEF) which results from diastolic dysfunction is a growing epidemiologic problem. However, the […]

Methods for predicting and treating cardiac dysfunction

Ageing myocardium undergoes structural and functional changes characterized by progressive cardiomyocyte hypertrophy, interstitial fibrosis and […]

Methods of treating heart failure

Worldwide, 1% to 2% of the general adult population have heart failure (HF), which is accompanied by reduced quality of life, high morbidity, […]

Methods and pharmaceutical compositions for the treatment of

The present invention relates to methods and pharmaceutical compositions for the treatment of age-related cardiometabolic diseases. In particular, the […]

Apelin analogs for the treatment of heart failure

The invention related to metabolically stable Apelin analogs and their use for the prevention or the treatment of diseases mediated by the apelin […]